Master
Content
Chagas disease is a primary focus area of research in our labs as well as the Vaccine Center. Chagas is a serious condition afflicting approximately 6 to 7 million people around the world. The disease is caused by a protozoal parasite called Trypanosoma cruzi, which is transmitted by a triatomine insect known as the kissing bug. Our specific areas of interest:
Heading
Vaccines
Content
- Tc-24 Chagas vaccine in clinical trials
- Vaccine-linked chemotherapy for human and veterinary use
- Jones et al.-- --PLOS Negl Trop Dis
- mRNA vaccines for malaria and other parasitic pathogens
- Versteeg, Pollet-- --Trends in mRNA Vaccine Research
- Poveda et al.-- --ACS Appl Mater Interfaces
- Vaccine antigen discovery
- Pollet et al.-- --Plos Pathog
Media Component
Heading
Kissing bugs
Content
Two kissing bugs (Triatomines) collected from a deer lease near Hallettsville, Texas
Heading
Diagnostics
Content
- Diagnostic antigen discovery
- Versteeg----ppt
- Assay development
- Mejia-- --pre-print under review Testing in
canines and humans - Mejia----ppt
- Mejia-- --pre-print under review Testing in
Heading
Therapeutics
Content
- Hookworm proteins as host-directed therapy
- Jones----ppt
- Probiotics to reduce the pathology of CD
- Poveda-- —Microbiol Spectr Poveda--
- Poveda----ACS Appl. Mater. Interfaces
Heading
Epidemiology
Content
- Epidemiologic, immunologic, and clinical consequences of CD
- Clark----Lancet Reg Health Am
- Chagas disease in the immunocompromised
- °ä±ô²¹°ù°ì—--Curr Op Inf Dis
- Clark----Clin Infect Dis
- Vectors and transmissions
- Gunter----Am J Trop Med Hyg
Heading
Pre-Clinical Studies
Content
- Vaccine-linked chemotherapy for human and veterinary use
- Jones et al.-- --PLOS Negl Trop Dis
- mRNA vaccines for malaria and other parasitic pathogens
- Versteeg, Pollet-- --Trends in mRNA Vaccine Research
- Poveda et al.-- --ACS Appl Mater Interfaces
- Vaccine antigen discovery
- Pollet et al.-- --Plos Pathog
